NFH I3C SAP 150mg 60 Caps
150 mg
Soy Free
Non GMO
Corn Free
Dairy Free
Yeast Free
Sugar Free
Starch Free
Wheat Free
Gluten Free
No preservatives
No artificial flavour or colour
Indole-3-carbinol (I3C) is a phytochemical derived in high concentrations from the Brassica family of vegetables, including broccoli, cauliflower, Brussels sprouts, and cabbage. I3C and its derivative compounds have been shown to exert immunomodulatory effects in the human body. I3C has been shown to exhibit direct antiestrogenic activity via competitive inhibition of estrogen receptors, upregulate the cytochrome P450 isoenzymes CYP1A1, CYP1A2, and CYP1B1, thereby increasing estrogen metabolism, and shift estrogen metabolism away from the more proliferative (16‑OHE1) towards the more protective (2‑OHE1) estrogen species.